Yes, it should work electrically, and potentially even with a simple adapter cable if you don't have a dock. The key questions would be a firmware version that is loading the appropriate driver (seems to be as indicated above) and rigging up whatever software you want to use.

As a note, if you didn't want to use a USB-serial cable, you could just use an inverting line receiver with 3.3v output and go right into one of the omega 2's hardware UARTs. This could likely be as simple as some resistors and an NPN transistor or NFET.