@WereCatf I do have things set up as you stated. Thank you for letting me know I didnt really state my issue. I have corrected my original post and added my wiring configuration.

So I have finally gotten around to putting my electronics into an enclosure and was attempting to connect to my RAMPS board though the USB+ and USB- on the expansion board due to space constraints as seen below.

Onion
Red => 5V
Grey => GND
blue =>USB-
Green=>USB+

Mega USB A
Red => 5V
Grey => GND
blue=> pin 2 (USB -)
Green=> pin 3 (USB +)

I power everything up through the Green Terminal Block on the Ramps Shield.

I am not able to connect to the Ramps board with this setup. The issue I have come across is that I cant seem to find any documentation on using the USB pins. Anyone have a resource I could read up on to get this working in this fashion?

https://drive.google.com/open?id=18u8v2-7UK3iKGmlZZ8UeBE3zajbIXJrsrA

Edit:

After attempting to connect through the normal USB A to the ramps it seems that the Omega is seeing the serial port

• [ 169.668429] usb 2-1: new full-speed USB device number 3 using ohci-platform
  [ 169.903385] cdc_acm 2-1:1.0: ttyACM0: USB ACM device

but Octoprint is not when connected through the pins.

So I am currently attempting to solve this issue in hopes that will also alleviate the above issue.

The error I am getting in the Octoprint Terminal is:

• Changing monitoring state from 'Offline' to 'Opening serial port'
  Connecting to: None
  Unexpected error while connecting to serial port: None SerialException: '[Errno 2] could not open port None: [Errno 2] No such file or directory: 'None'' @ comm.py:_openSerial:795
  Changing monitoring state from 'Opening serial port' to 'Error: Failed to open seria...'

@Florian-Knodt Yesterday I tried to use the given ip with the port and got nothing. Today, well today is another day. Plug her in and go directly to the octo-print front page. Thank you for the quick response.

First, thank you for this step by step instruction.

After finally getting everything done I am running octoprint but does not come up with an appropriate ip address!

root@Omega-6255:~/OctoPrint-1.0.0# ./run
2017-02-16 06:56:10,251 - octoprint.server - INFO - Listening on http://0.0.0.0:5000

When I kill octoprint I get.

^C2017-02-16 06:57:04,868 - octoprint.server - CRITICAL - Now that is embarrassing... Something really really went wrong here. Please report this including the stacktrace below in OctoPrint's bugtracker. Thanks!
2017-02-16 06:57:04,871 - octoprint.server - ERROR - Stacktrace follows:
Traceback (most recent call last):
File "/root/OctoPrint-1.0.0/src/octoprint/server/init.py", line 190, in run
IOLoop.instance().start()
File "/usr/lib/python2.7/site-packages/tornado/ioloop.py", line 627, in start
event_pairs = self._impl.poll(poll_timeout)
KeyboardInterrupt

I conclude that I am missing something or it really is a bug either in my build or in the octoprint ( which I doubt due to others having theirs up and running.) Not sure where to go here. I've attempted to use my googlefu and rebooted 2 times. I have access to the Onion from local ip of 192...72 and though USB. I am also connected to the internet so I am totally confused here. Any help would be much appreciated