I know the last reply to this topic is from nearly a year ago, but just wanted to report that I just installed OctoPrint v1.3.9 on my Omega2+ with the latest 0.2.1 (b199) firmware (had 0.2 or the last of the 0.1 line and OctoPrint 1.0.0 when I used it last), and it seems to be working fine with my Kodama Trinus printer just fine... Thanks to all the posters who suggested the swap memory, python-dev/gcc and octoprint serve --iknowwhatimdoing workarounds / updates to the instructions... after some fumbling around I was able get it all working! ;)