Hi Boken Lin,
Thanks for your reply and yes I would like to see if it would be possible to cross-compile smbus-cffi on the Omega. smbus-cffi according to their site is just "cffi (C foreign function interface)-based python reimplementation of the python-smbus C-extension" : https://pypi.python.org/pypi/smbus-cffi
and the only reason that I'm interested in this module is just because It's one of the requirements for installing TSL2591 module.
It'll be awesome if there would a work around to compile this module somehow...Thanks.