@Michael-Hebert if you mean panel like this https://www.adafruit.com/product/420 then I think you can not. This is not SPI device but "12 16-bit latches that allow you to drive the display with a 1:8 scan rate." as described by Adafruit. Also, "Keep in mind that these displays are designed to be driven by FPGAs or other high speed processors: they do not have built in PWM control of any kind." "you'll need 12 digital pins, and about 800 bytes of RAM to buffer the 12-bit color image." Without own driver/controller this panel is silly device.
As an idea only - try to use Arduino based board and Adafruit library as panel controller, and Omega2 as main unit and communicate them using SPI, I2C or UART.